On a Population Level, Genetic Mutations in Sperm Increase As Men Age and their Offspring Suffer As A Result of Ignoring This Fact
Don't be fooled by the lack of a public discussion. There is NO doubt that genetic disorders of all kinds increase in offspring with the age of the father and the age of the mother's father at her birth because there is a male biological clock and advancing paternal age equals more DNA mutations as sperm divide from the sperm stem cells. Nothing is simple and one has to look at the glaring evidence in the papers written by honest scientists that have been published since the 1950s. You will also find dishonesty among some scientists trying to cover up this biological truth. Also read about vaccinations and their effects in this blog.
SHORT REPORT
Advanced paternal age: How old is too old? Isabelle Bray, David Gunnell, George Davey Smith
Department of Social Medicine, University of Bristol, UK
Correspondence to:Correspondence to: Dr I Bray Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK; Issy.Bray@bristol.ac.uk
"The mean age of fathers in England and Wales increased from 29.2 years in 1980 to 32.1 in 2002.6 The public health implications of this trend have not been ... "more schizophrenia, more birth defects, more diabetes, more autism etc.etc.
Average paternal age in the UK is increasing. The public health implications of this trend have not been widely anticipated or debated. This commentary aims to contribute to such a debate. Accumulated chromosomal aberrations and mutations occurring during the maturation of male germ cells are thought to be responsible for the increased risk of certain conditions with older fathers. Growing evidence shows that the offspring of older fathers have reduced fertility and an increased risk of birth defects, some cancers, and schizophrenia. Adverse health outcomes should be weighed up against advantages for children born to older parents, mindful that these societal advantages are likely to change over time.
Keywords: paternal age; DNA damage; fertility; abnormalities; schizophrenia
Labels: Average paternal age has increased, father's age and risk of autism/schizophrenia/neurocognitive disorders
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