AUTISM PREVENTION FATHER BABIES 24-34 PATERNAL AGE IS KEY IN NON-FAMILIAL AUTISMVaccines: POSSIBILITY THAT PATERNAL SMOKING CAUSES MUTATIONS IN SPERM THAT LEAD TO CANCER, BIRTH DEFECTS, GENETIC DISEASES IN OFFSPRING DNA DAMAGE UP 50%

AUTISM PREVENTION FATHER BABIES 24-34 PATERNAL AGE IS KEY IN NON-FAMILIAL AUTISMVaccines

"It is very possible that PATERNAL AGE is the major predictor of(non-familial) autism." Harry Fisch, M.D., author "The Male Biological Clock". Sperm DNA mutates and autism, schizophrenia bipolar etc. results. What is the connection with autoimmune disorders? Having Type 1 diabetes, SLE,etc. in the family, also if mother had older father. NW Cryobank will not accept a sperm donor past 35th BD to minimize genetic abnormalities.VACCINATIONS also cause autism.

Friday, May 25, 2007

POSSIBILITY THAT PATERNAL SMOKING CAUSES MUTATIONS IN SPERM THAT LEAD TO CANCER, BIRTH DEFECTS, GENETIC DISEASES IN OFFSPRING DNA DAMAGE UP 50%

1: Mutat Res. 1996 Apr 13;351(2):199-203. Links
Smoking and low antioxidant levels increase oxidative damage to sperm DNA.Fraga CG, Motchnik PA, Wyrobek AJ, Rempel DM, Ames BN.
Fisicoquimica, Facultad de Farmacia y Bioquimica, Universidad de BuenosAires, Argentina.

Our previous studies have shown that men with low ascorbate intake have markedly increased oxo8dG in the DNA of their sperm. Because cigarette smoke is high in oxidants and depletes plasma and tissue antioxidants, oxidative DNA damage in sperm and tocopherol and ascorbate levels in seminal plasma were determined in smokers and non-smokers. The level in sperm DNA of oxo8dG, an oxidative lesion of guanine, was 50% higher in smokers compared to nonsmokers (p = 0.005). The concentration of alpha-tocopherol in seminal plasma was decreased in smokers by 32% (p = 0.03). Smoking and low antioxidant levels increase oxidative damage to sperm DNA. We discuss the possibility that paternal smoking causes mutations in sperm that lead to cancer, birth defects, and genetic diseases in offspring.

PMID: 8622715 [PubMed - indexed for MEDLINE]

Labels: paternal smoking causes DNA mutations in sperm. cigarette smoking