"It is very possible that PATERNAL AGE is the major predictor of(non-familial) autism." Harry Fisch, M.D., author "The Male Biological Clock". Sperm DNA mutates and autism, schizophrenia bipolar etc. results. What is the connection with autoimmune disorders? Having Type 1 diabetes, SLE,etc. in the family, also if mother had older father. NW Cryobank will not accept a sperm donor past 35th BD to minimize genetic abnormalities.VACCINATIONS also cause autism.

Saturday, December 15, 2007

"However, parents-to-be should recognize that younger adulthood is the best time for both sexes to have children."

Dr. Simeon Margolis, a professor of both medicine and biological chemistry at the Johns Hopkins School of Medicine.

"DNA damage in sperm is one probable explanation for the genetic abnormalities associated with fatherhood at an older age. The testicular cells that give rise to sperm divide every 16 days; this means that the cells will have split about 840 times by age 50, and with each cell division the chance increases for errors in the sperm's DNA. Examination of sperm from men ages 22 to 80 showed a progressive increase with age in the number of broken DNA strands and other genetic abnormalities"



At 12:27 PM, Blogger Banjo Time said...

You haven't updated in awhile, so I wanted to tip you off to this news report from yesterday:,1,5081058.story?coll=la-health-medicine

Here's paragraph 4:

The genetic defect was found in children with autism but not in their parents, indicating that it was a spontaneous mutation that occurred sometime after fertilization. The location, called 16p11.2, is what is known as a genetic "hot spot," meaning it is unusually susceptible to such mutations.

At 12:29 PM, Blogger Banjo Time said...

(In case the link is showing up cut off for you too.)

At 7:43 PM, Blogger concerned heart said...

Thank you Banjo Time and please add to this blog as I have been unable to do so. Your story about the finding of the spontaneous (de novo) mutation in autism is crucial to understanding that autism is very often non-familial and due to the spontaneous sperm mutations and the age of the dad at conception.


Post a Comment

Links to this post:

Create a Link

<< Home

Top Autism Sites Health Blogs -  Blog Catalog Blog Directory StumbleUpon Toolbar Stumble It! blog directory PageRank Button Add to Technorati Favorites Health Blogs
Directory of Health Blogs Blogarama - The Blog Directory