"It is very possible that PATERNAL AGE is the major predictor of(non-familial) autism." Harry Fisch, M.D., author "The Male Biological Clock". Sperm DNA mutates and autism, schizophrenia bipolar etc. results. What is the connection with autoimmune disorders? Having Type 1 diabetes, SLE,etc. in the family, also if mother had older father. NW Cryobank will not accept a sperm donor past 35th BD to minimize genetic abnormalities.VACCINATIONS also cause autism.

Friday, March 18, 2011

[Recent progress of epidemiological research in search of the aetiology of autism].

Nihon Shinkei Seishin Yakurigaku Zasshi. 2011 Feb;31(1):29-34.

[Recent progress of epidemiological research in search of the aetiology of autism].
[Article in Japanese]

Tsuchiya KJ, Matsumoto K, Takei N.

Research Center for Child Mental Development, Hamamatsu University School of Medicine, Handayama 1-20-1 Higashiku, Hamamatsu, 431-3192 Japan.

Autism and autism spectrum disorders (ASDs) are neurodevelopmental disorders characterised by the behavioral traits of impaired social cognition and communication, and repetitive and/or obsessive behaviour and interests. Studies point towards increased prevalence of autism/ASD. However, no treatment or prevention for the disorder has been established, since the aetiological pathway of this disorder remains largely unknown. Considering this lack of knowledge, epidemiological studies are expected to give clues for a better understanding of the disorder. As such, advanced paternal age at birth and low birthweight (or intrauterine growth retardation) have been reported to be candidate risk factors. These findings allow us to propose novel research strategies in search of the aetiology of autism/ASD. Following this trend, the authors initiated a research project, "the Hamamatsu Birth Cohort for Mothers and Children (HBC)", seeking risk factors for autism/ASD extensively. The HBC is expected to enroll 1,200 dyads of mother and child and to follow them until the child becomes 4 years of age.



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