We also note that schizophrenia and autism share certain risk factors such as advanced paternal age
We also note that schizophrenia and autism share certain risk factors such as advanced paternal age. Apart from genomic imprinting, copy number variants related to advanced paternal age may also contribute to the differential trajectory of brain development associated with autism and schizophrenia
: Behav Brain Sci. 2008 Jun;31(3):264-265.
Animal models may help fractionate shared and discrete pathways underpinning schizophrenia and autism.Burne TH, Eyles DW, McGrath JJ.
Queensland Centre for Mental Health Research, The Queensland Brain Institute, The University of Queensland, St Lucia, Brisbane, 4072, Australia. t.burne@uq.edu.au http://www.qbi.uq.edu.au eyles@uq.edu.au http://www.qbi.uq.edu.au john_mcgrath@qcmhr.uq.edu.au http://www.qbi.uq.edu.au.
Crespi & Badcock (C&B) present an appealing and parsimonious synthesis arguing that schizophrenia and autism are differentially regulated by maternal versus paternal genomic imprinting, respectively. We argue that animal models related to schizophrenia and autism provide a useful platform to explore the mechanisms outlined by C&B. We also note that schizophrenia and autism share certain risk factors such as advanced paternal age. Apart from genomic imprinting, copy number variants related to advanced paternal age may also contribute to the differential trajectory of brain development associated with autism and schizophrenia.
Labels: We also note that schizophrenia and autism share certain risk factors such as advanced paternal age
1 Comments:
Thanks for the information on the link between autism and schizophrenia. That is very fascinating that those two diseases share a parental age.
We recently wrote an article on schizophrenia medication at Brain Blogger. A study from Harvard recently showed that restrictive drug programs might cause schizophrenia patients to stop taking their medications and nearly 80% of patients without antipsychotic medication will have a serious reoccurrence of their illness within a year. So should schizophrenic patients receive free medications?
We would like to read your comments on our article. Thank you.
Sincerely,
Kelly
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