Will Researchers Look For Copy Number Variations in the Sperm Making Cells of Fathers of children with CNVs?

The groundbreaking research finding CNVs in some children with sporadic autism has been published. Will the researchers look at the sperm and spermatagonia of the fathers of these children along with all the other fathers and control group?


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This paper summarized chromosome regions known to be associated
with autism phenotype. 15q11.2, 2qter and 22qter represent the most
frequent loci.
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hybridization identifies high frequency of cryptic
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Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T,
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association of de novo copy number mutations with autism.
Science 2007, in press.
The application of a genome-wide array CGH with 85 000 oligonucleotide
probes (ROMA) (see [27]) in 165 families with autism showed a statistically
significant association of de novo CNV.